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Current Faculty

Zhen Fang, Lecturer

By :    Date : 2011-06-26 00:00:00    View :



Dr. Zhen Fang



Education
Ph.D. School of Biotechnology, Jiangnan University, 2016
Visiting Scholar, Chemical and Biological Engineering, Rensselaer Polytechnic Institute, 01/2016-07/2016
B.S. School of Biotechnology, Jiangnan University, 2011

Research Interests
Protein engineering and rational design of new functional enzymes;
Synthetic biology and metabolic engineering to efficiently yield natural products;
Light-driven or electric-driven H2 production and CO2 reduction using biohybrid;
The mechanism of electron reverse transport and NADH/ATP regeneration in microbial cell.

Publications:
1. Fang, Z., Zhang, J., Liu, B., Du, G., & Chen, J. (2016). Enhancement of the catalytic efficiency and thermostability of Stenotrophomonas sp. keratinase KerSMD by domain exchange with KerSMF. Microbial biotechnology, 9(1), 35-46.
2. Fang, Z., Zhang, J., Du, G., & Chen, J. (2016). Improved catalytic efficiency, thermophilicity, anti-salt and detergent tolerance of keratinase KerSMD by partially truncation of PPC domain. Scientific reports, 6.
3. Fang, Z., Zhang, J., Liu, B., Du, G., & Chen, J. (2015). Insight into the substrate specificity of keratinase KerSMD from Stenotrophomonas maltophilia by site-directed mutagenesis studies in the S1 pocket. RSC Advances, 5(91), 74953-74960.
4. Fang, Z., Zhang, J., Liu, B., Jiang, L., Du, G., & Chen, J. (2014). Cloning, heterologous expression and characterization of two keratinases from Stenotrophomonas maltophilia BBE11-1. Process Biochemistry, 49(4), 647-654.
5. Liu, B., Zhang, J., Fang, Z., Du, G., Chen, J., & Liao, X. (2014). Functional analysis of the C-terminal propeptide of keratinase from Bacillus licheniformis BBE11-1 and its effect on the production of keratinase in Bacillus subtilis. Process Biochemistry, 49(9), 1538-1542.
6. Fang, Z., Zhang, J., Liu, B., Du, G., & Chen, J. (2013). Biodegradation of wool waste and keratinase production in scale-up fermenter with different strategies by Stenotrophomonas maltophilia BBE11-1. Bioresource technology, 140, 286-291.
7. Fang, Z., Zhang, J., Liu, B., Du, G., & Chen, J. (2013). Biochemical characterization of three keratinolytic enzymes from Stenotrophomonas maltophilia BBE11-1 for biodegrading keratin wastes. International Biodeterioration & Biodegradation, 82, 166-172.
8. Liu, B., Zhang, J., Fang, Z., Gu, L., Liao, X., Du, G., & Chen, J. (2013). Enhanced thermostability of keratinase by computational design and empirical mutation. Journal of industrial microbiology & biotechnology, 40(7), 697-704.

Tel: 0511-88786708, Email: zhenfang89@hotmail.com

Last :Yang-Yang Yu, Ph.D., Associate Professor