Title: Biotechnology
Paradigm Shift: From Living Microorganisms to Cell-Free Biomanufacturing
Speaker: Prof. Dr.
Y.-H. Percival Zhang, Virginia Tech, USA
Date: May 26, 2014, 10 am
Venue: The 2nd Meeting
Room, Meeting Center of Jiangsu University
Dr. Zhang
is a full Professor of Virginia Tech, USA, and serves as associate editor
of “energy Science & Engineering” and “PLoS One”. Prof. Zhang has published
more than 100 peer-reviewed papers in famous journals including PNAS, Nature
Communication, and Angew Chem. His publications have got over 3000 citations
and have H-index of 31. The mission of his Lab is to solve key problems
associated with the sustainability revolution through out-of-the-box solutions,
which are based on well-known technologies while look like crazy ideas. He plan
to construct the electricity-carbohydrate-hydrogene (ECHo) cycle using
cell-free biomanufacturing system. His talk will introduce the concept of this
disruptive technology platform, present its four major applications: (i) the
highest yield production of hydrogen for C5 and C6 sugars [2]; (ii) enzymatic transformation
of cellulose to amylose, a value-added co-product [3]; (iii) the generation of
electricity via a sugar biobattery [4], and (iv) CO2
fixation; and as well as develop building blocks- synthetic metabolons [5] and engineered redox enzymes
working on biomimetic cofatcors.